preparation and characterization of tri-block poly(lactide)- poly(ethylene glycol)- poly (lactide) nanoparticles for sustained release of rivastigmine

preparation and characterization of poly(e-caprolactone)–poly(ethylene glycol) – poly(e-caprolactone) nanoparticles for sustained release of tamoxifen

Adriamycin release from poly(lactide-co-glycolide)-polyethylene glycol nanoparticles: synthesis, and in vitro characterization

The preparation, properties, and application in adriamycin delivery ofbiocompatible and biodegradable poly(lactide-co-glycolide)-polyethylene glycol (PLGA-PEG) nanoparticles are discussed. PLGA-PEG copolymers were synthesized by ring opening polymerization of the dl-lactide and glycolide in the presence of PEG1000. 1H-NMR and FT-IR spectrum were consistent with the structure of PLGA-PEG copolym...

preparation of atorvastatin-loaded polylactide-poly(ethylene glycol)-polylactide tri-block copolymer polymersomes and evaluation of drug release behaviors in vitro

Preparation and Physicochemical Characterization of Poly (D, L-lactide-co-glycolide) Nanoparticles for Controlled Release of EGCG

Chemoprevention, especially through the use of naturally occurring phytochemicals capable of impeding the process of one or more steps of carcinogenesis, is a promising approach for cancer management. Despite promising results in preclinical settings, its applicability to humans has met with limited success largely due to inefficient systemic delivery and bioavailability of chemopreventive agen...

Preparation, characterization, and safety evaluation of poly(lactide-co-glycolide) nanoparticles for protein delivery into macrophages

Following infection, HIV establishes reservoirs within tissues that are inaccessible to optimal levels of antiviral drugs or within cells where HIV lies latent, thus escaping the action of anti-HIV drugs. Macrophages are a persistent reservoir for HIV and may contribute to the rebound viremia observed after antiretroviral treatment is stopped. In this study, we further investigate the potential...

Poly(lactide-co-glycolide) microparticles as systems for controlled release of proteins -- preparation and characterization.

Poly(DL-lactide-co-glycolide) (PDLLGA) and poly(L-lactide-co-glycolide) (PLLGA) copolymers were prepared by bulk ring opening polymerization of lactide and glycolide and characterized by GPC, FTIR, 1H NMR and DSC. Copolymers with different molar masses at a constant lactide/glycolide ratio were used for preparation of bovine serum albumin (BSA)-loaded microparticles by the double emulsion w/o/w...